Archives of Clinical Infectious Diseases

Published by: Kowsar

Disseminated Nocardiosis in an Immunocompetent Individual Infected with Nocardia brasiliensis, an Opportunistic Agent

Massoud Mardani 1 , Narges Aslani 2 , Mohsen Geramishoar 3 , Sadegh Khodavaisy 3 , Sahar Mohseni 4 and Hamid Badali 5 , *
Authors Information
1 Infectious Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
3 Department of Medical Mycology and Parasitology, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Microbiology, Sari Branch, Islamic Azad University, Sari, Iran
5 Department of Medical Mycology and Parasitology /Invasive Fungi Research Centre (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Article information
  • Archives of Clinical Infectious Diseases: January 2017, 12 (1); e37738
  • Published Online: December 25, 2016
  • Article Type: Case Report
  • Received: March 11, 2016
  • Revised: December 7, 2016
  • Accepted: December 18, 2016
  • DOI: 10.5812/archcid.37738

To Cite: Mardani M, Aslani N, Geramishoar M, Khodavaisy S, Mohseni S, et al. Disseminated Nocardiosis in an Immunocompetent Individual Infected with Nocardia brasiliensis, an Opportunistic Agent, Arch Clin Infect Dis. 2017 ; 12(1):e37738. doi: 10.5812/archcid.37738.

Copyright © 2016, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Wilson JW. Nocardiosis: updates and clinical overview. Mayo Clin Proc. 2012; 87(4): 403-7[DOI][PubMed]
  • 2. Schlaberg R, Huard RC, Della-Latta P. Nocardia cyriacigeorgica, an emerging pathogen in the United States. J Clin Microbiol. 2008; 46(1): 265-73[DOI][PubMed]
  • 3. Hu Y, Zheng D, Takizawa K, Mikami Y, Dai L, Yazawa K, et al. Systemic nocardiosis caused by Nocardia concava in China. Med Mycol. 2011; 49(6): 662-6[DOI][PubMed]
  • 4. Cassir N, Million M, Noudel R, Drancourt M, Brouqui P. Sulfonamide resistance in a disseminated infection caused by Nocardia wallacei: a case report. J Med Case Rep. 2013; 7: 103[DOI][PubMed]
  • 5. Yamaguchi H, Sekimoto E, Shirakami A, Shibata H, Ozaki S, Shigekiyo T, et al. Testicular nocardiosis accompanied by cutaneous lesions in an immunocompetent man. Intern Med. 2013; 52(1): 129-33[PubMed]
  • 6. Agterof MJ, van der Bruggen T, Tersmette M, ter Borg EJ, van den Bosch JM, Biesma DH. Nocardiosis: a case series and a mini review of clinical and microbiological features. Neth J Med. 2007; 65(6): 199-202[PubMed]
  • 7. Munoz J, Mirelis B, Aragon LM, Gutierrez N, Sanchez F, Espanol M, et al. Clinical and microbiological features of nocardiosis 1997-2003. J Med Microbiol. 2007; 56: 545-50[DOI][PubMed]
  • 8. Conville PS, Witebsky FG. Multiple copies of the 16S rRNA gene in Nocardia nova isolates and implications for sequence-based identification procedures. J Clin Microbiol. 2005; 43(6): 2881-5[DOI][PubMed]
  • 9. Leitner E, Valentin T, Hoenigl M, Lanz P, Flick H, Zollner-Schwetz I, et al. First report of Nocardia asiatica olecranon bursitis in an immunocompetent traveler returning to Austria. J Clin Microbiol. 2013; 51(7): 2461-2[DOI][PubMed]
  • 10. Klindworth A, Pruesse E, Schweer T, Peplies J, Quast C, Horn M, et al. Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies. Nucleic Acids Res. 2013; 41(1): 1[DOI][PubMed]
  • 11. Glupczynski Y, Berhin C, Janssens M, Wauters G. Determination of antimicrobial susceptibility patterns of Nocardia spp. from clinical specimens by Etest. Clin Microbiol Infect. 2006; 12(9): 905-12[DOI][PubMed]
  • 12. Luo Q, Hiessl S, Poehlein A, Daniel R, Steinbuchel A. Insights into the microbial degradation of rubber and gutta-percha by analysis of the complete genome of Nocardia nova SH22a. Appl Environ Microbiol. 2014; 80(13): 3895-907[DOI][PubMed]
  • 13. Kageyama A, Poonwan N, Yazawa K, Mikami Y, Nishimura K. Nocardia beijingensis, is a pathogenic bacterium to humans: the first infectious cases in Thailand and Japan. Mycopathologia. 2004; 157(2): 155-61[PubMed]
  • 14. Saubolle MA, Sussland D. Nocardiosis: review of clinical and laboratory experience. J Clin Microbiol. 2003; 41(10): 4497-501[PubMed]
  • 15. Hardak E, Yigla M, Berger G, Sprecher H, Oren I. Clinical spectrum and outcome of Nocardia infection: experience of 15-year period from a single tertiary medical center. Am J Med Sci. 2012; 343(4): 286-90[DOI][PubMed]
  • 16. Flateau C, Jurado V, Lemaitre N, Loiez C, Wallet F, Saiz-Jimenez C, et al. First case of cerebral abscess due to a novel Nocardia species in an immunocompromised patient. J Clin Microbiol. 2013; 51(2): 696-700[DOI][PubMed]
  • 17. Hui CH, Au VW, Rowland K, Slavotinek JP, Gordon DL. Pulmonary nocardiosis re-visited: experience of 35 patients at diagnosis. Respir Med. 2003; 97(6): 709-17[PubMed]
  • 18. Alijani N, Mahmoudzadeh S, Hedayat Yaghoobi M, Geramishoar M, Jafari S. Multiple brain abscesses due to nocardia in an immunocompetent patient. Arch Iran Med. 2013; 16(3): 192-4[PubMed]
  • 19. Chedid MB, Chedid MF, Porto NS, Severo CB, Severo LC. Nocardial infections: report of 22 cases. Rev Inst Med Trop Sao Paulo. 2007; 49(4): 239-46[PubMed]
  • 20. Taj-Aldeen SJ, Deshmukh A, Doiphode S, Wahab AA, Allangawi M, Almuzrkchi A, et al. Molecular identification and susceptibility pattern of clinical Nocardia species: Emergence of Nocardia crassostreae as an agent of invasive nocardiosis. Can J Infect Dis Med Microbiol. 2013; 24(2): 33-8[PubMed]
  • 21. Mirhendi H, Fatemi MJ, Bateni H, Hajabdolbaghi M, Geramishoar M, Ahmadi B, et al. First case of disseminated phaeohyphomycosis in an immunocompetent individual due to Alternaria malorum. Med Mycol. 2013; 51(2): 196-202[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments