Archives of Clinical Infectious Diseases

Published by: Kowsar

Four-Month-Old Boy With Fever, Hepatosplenomegaly and Diffuse Pulmonary Infiltrations

Fariba Shirvani 1 , * , Zahra Chavoshzadeh 1 , Reza Arjmand 1 and Abdollah Karimi 1
Authors Information
1 Pediatric Infectious Diseases Research Center (PIRC), Mofid Children Hospital, Shahid Beheshti University of Medical sciences, Tehran, IR Iran
Article information
  • Archives of Clinical Infectious Diseases: April 28, 2012, 7 (2); e13947
  • Published Online: April 13, 2012
  • Article Type: Case Report
  • Received: January 5, 2012
  • Revised: January 9, 2012
  • Accepted: February 21, 2012
  • DOI: 10.5812/archcid.13947

To Cite: Shirvani F, Chavoshzadeh Z, Arjmand R, Karimi A. Four-Month-Old Boy With Fever, Hepatosplenomegaly and Diffuse Pulmonary Infiltrations, Arch Clin Infect Dis. 2012 ; 7(2):e13947. doi: 10.5812/archcid.13947.

Copyright © 2012, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Conclusions
  • 1. World Health Organization, BCG vaccine. WHO position paper. Wkly Epidemiol Rec. 2004; 79: 27-38
  • 2. Fitoz S, Ikinciogullari A, Dogan BE, Babacan E, Atasoy C, Sahin G. Bacillus Calmette-Guerin osteomyelitis in a patient with severe combined immunodeficiency: radiologic appearances of extensive dissemination. Current Problems in Diagnostic Radiology. 2004; 33(1): 25-7
  • 3. Sadeghi-Shabestari M, Rezaei N. Disseminated bacille Calmette-Guérin in Iranian children with severe combined immunodeficiency. International Journal of Infectious Diseases. 2009; 13(6)
  • 4. Lotte A, Waxz-Hockert O, Poisson N. Complications induced by BCG vaccination: A retrospective study. Bull Int Union Tuberc. 1978; 53(114)
  • 5. Rezaei N, Aghamohammadi A, Moin M, Pourpak Z, Movahedi M, Gharagozlou M, et al. Frequency and clinical manifestations of patients with primary immunodeficiency disorders in Iran: update from the Iranian Primary Immunodeficiency Registry. J Clin Immunol. 2006; 26(6): 519-32[DOI][PubMed]
  • 6. Huang LH, Shyur SD, Weng JD, Shin C, Huang FY, Tzen CY. Disseminated cutaneous bacille Calmette-Guerin infection identified by polymerase chain reaction in a patient with X-linked severe combined immunodeficiency. Pediatr Dermatol. 2006; 23(6): 560-3[DOI][PubMed]
  • 7. Yeganeh M, Heidarzade M, Pourpak Z, Parvaneh N, Rezaei N, Gharagozlou M, et al. Severe combined immunodeficiency: a cohort of 40 patients. Pediatr Allergy Immunol. 2008; 19(4): 303-6[DOI][PubMed]
  • 8. Movahedi M, Aghamohammadi A, Rezaei N, Shahnavaz N, Jandaghi AB, Farhoudi A, et al. Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registry. Int Arch Allergy Immunol. 2004; 134(3): 253-9[DOI][PubMed]
  • 9. Bustamante J, Aksu G, Vogt G, de Beaucoudrey L, Genel F, Chapgier A, et al. BCG-osis and tuberculosis in a child with chronic granulomatous disease. J Allergy Clin Immunol. 2007; 120(1): 32-8[DOI][PubMed]
  • 10. Reichenbach J, Rosenzweig S, Doffinger R, Dupuis S, Holland SM, Casanova JL. Mycobacterial diseases in primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2001; 1(6): 503-11[PubMed]
  • 11. Filipe-Santos O, Bustamante J, Chapgier A, Vogt G, de Beaucoudrey L, Feinberg J, et al. Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features. Semin Immunol. 2006; 18(6): 347-61[DOI][PubMed]
  • 12. Moin M, Farhoudi A, Movahedi M, Rezaei N, Pourpak Z, Yeganeh M, et al. The clinical and laboratory survey of Iranian patients with hyper-IgE syndrome. Scand J Infect Dis. 2006; 38(10): 898-903[DOI][PubMed]
  • 13. Grunebaum E, Zhang J, Dadi H, Roifman CM. Haemophagocytic lymphohistiocytosis in X-linked severe combined immunodeficiency. Br J Haematol. 2000; 108(4): 834-7[PubMed]
  • 14. Joshi R, Phatarpekar A, Currimbhoy Z, Desai M. Haemophagocytic lymphohistiocytosis: a case series from Mumbai. Ann Trop Paediatr. 2011; 31(2): 135-40[DOI][PubMed]
  • 15. Shivanthan MC, Wijesiriwardena B, Jayaratne B, Gunasekara D, Biyanwila C, Wakawwatta A. Diagnosis of haemophagocytic lymphohistiocytosis in a resource-limited setting. Galle Medical Journal. 2011; 16(1): 44-6
  • 16. Kliegman RM, Behrman RE, Nelson WWE, Jenson HB. Nelson Textbook of Pediatrics. 2007;
  • 17. Tastan Y, Arvas A, Demir G, Alikasifoglu M, Gur E, Kiray E. Influence of Bacillus Calmette-Guerin vaccination at birth and 2 months old age on the peripheral blood T-cell subpopulations [gamma/delta and alpha-beta T cell]. Pediatr Allergy Immunol. 2005; 16(8): 624-9[DOI][PubMed]
  • 18. Khazaei HA, Rezaei N, Bagheri GR, Dankoub MA, Shahryari K, Tahai A, et al. Epidemiology of tuberculosis in the Southeastern Iran. Eur J Epidemiol. 2005; 20(10): 879-83[DOI][PubMed]
  • 19. Stephan JL, Vlekova V, Deist FL, Blanche S, Donadieu J, Saint-Basile GD, et al. Severe combined immunodeficiency: A retrospective single-center study of clinical presentation and outcome in 117 patients. The Journal of pediatrics. 1993; 123(4): 564-72
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