Archives of Clinical Infectious Diseases

Published by: Kowsar

Prevalence and Molecular Determination of Hepatitis C Infection in Khyber Pakhtunkhwa, Pakistan

Muhammad Waqar 1 , 2 , * , Asad Ullah Khan 3 , Amjad Ali 4 , Muhammad Wasim 5 , Muhammad Idrees 6 , Zobia Ismail 2 , Agha Asad Noor 1 , Noorul Akbar 7 , Shaista Bano 1 , Muhammad Arif Khan 8 and Rahim Ullah Khan 9
Authors Information
1 Department of Microbiology, University of Sindh, Jamshoro, Pakistan
2 Genome Centre for Molecular Based Diagnostics & Research (GCMBDR) Lahore, Pakistan
3 Department of Microbiology, Hazara University, Mansehra, Pakistan
4 Department of Biotechnology University of Malakand Chakdara Dir (lower) , Malakand, Pakistan
5 Department of Medicine, Khyber Medical College, Peshawar, Pakistan
6 Division of Molecular Virology, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan
7 Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan
8 Departments of Medicine, District Head Quarter Hospital, Mardan, Pakistan
9 Department of Pharmacy, University of Sindh, Jamshoro, Pakistan
Article information
  • Archives of Clinical Infectious Diseases: June 30, 2014, 9 (3); e17275
  • Published Online: June 25, 2014
  • Article Type: Research Article
  • Received: December 29, 2013
  • Accepted: January 20, 2014
  • DOI: 10.5812/archcid.17275

To Cite: Waqar M, Khan A U, Ali A, Wasim M, Idrees M, et al. Prevalence and Molecular Determination of Hepatitis C Infection in Khyber Pakhtunkhwa, Pakistan, Arch Clin Infect Dis. 2014 ; 9(3):e17275. doi: 10.5812/archcid.17275.

Abstract
Copyright © 2014, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, et al. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team. N Engl J Med. 1992; 327(27): 1899-905[DOI][PubMed]
  • 2. Bradley DW. Studies of non-A, non-B hepatitis and characterization of the hepatitis C virus in chimpanzees. Curr Top Microbiol Immunol. 2000; 242: 1-23[PubMed]
  • 3. Baldo V, Baldovin T, Trivello R, Floreani A. Epidemiology of HCV infection. Curr Pharm Des. 2008; 14(17): 1646-54[PubMed]
  • 4. Othman BM, Monem FS. Prevalence of hepatitis C virus antibodies among health care workers in Damascus, Syria. Saudi Med J. 2001; 22(7): 603-5[PubMed]
  • 5. Bakir TMF. Age-specific prevalence of antibody to hepatitis C virus among the Saudi population. Saudi Med J. 1992; 24(7): 321-4
  • 6. Said RA, Hamzeh YY, Mehyar NS, Rababah MS. Hepatitis C virus infection in hemodialysis patients in jordan. Saudi J Kidney Dis Transpl. 1995; 6(2): 140-3[PubMed]
  • 7. Ohno O, Mizokami M, Wu RR, Saleh MG, Ohba K, Orito E, et al. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J Clin Microbiol. 1997; 35(1): 201-7[PubMed]
  • 8. Bartenschlager R, Lohmann V. Replication of hepatitis C virus. J Gen Virol. 2000; 81: 1631-48[PubMed]
  • 9. Zein NN, Rakela J, Krawitt EL, Reddy KR, Tominaga T, Persing DH. Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group. Ann Intern Med. 1996; 125(8): 634-9[PubMed]
  • 10. McOmish F, Yap PL, Dow BC, Follett EA, Seed C, Keller AJ, et al. Geographical distribution of hepatitis C virus genotypes in blood donors: an international collaborative survey. J Clin Microbiol. 1994; 32(4): 884-92[PubMed]
  • 11. Dusheiko G, Main J, Thomas H, Reichard O, Lee C, Dhillon A, et al. Ribavirin treatment for patients with chronic hepatitis C: results of a placebo-controlled study. J Hepatol. 1996; 25(5): 591-8[PubMed]
  • 12. Nousbaum JB, Pol S, Nalpas B, Landais P, Berthelot P, Brechot C. Hepatitis C virus type 1b (II) infection in France and Italy. Collaborative Study Group. Ann Intern Med. 1995; 122(3): 161-8[PubMed]
  • 13. Takada N, Takase S, Takada A, Date T. Differences in the hepatitis C virus genotypes in different countries. J Hepatol. 1993; 17(3): 277-83[PubMed]
  • 14. Abdulkarim AS, Zein NN, Germer JJ, Kolbert CP, Kabbani L, Krajnik KL, et al. Hepatitis C virus genotypes and hepatitis G virus in hemodialysis patients from Syria: identification of two novel hepatitis C virus subtypes. Am J Trop Med Hyg. 1998; 59(4): 571-6[PubMed]
  • 15. Chamberlain RW, Adams N, Saeed AA, Simmonds P, Elliott RM. Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East. J Gen Virol. 1997; 78 ( Pt 6): 1341-7[PubMed]
  • 16. Simmonds P, Holmes EC, Cha TA, Chan SW, McOmish F, Irvine B, et al. Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region. J Gen Virol. 1993; 74 ( Pt 11): 2391-9[PubMed]
  • 17. Cha TA, Kolberg J, Irvine B, Stempien M, Beall E, Yano M, et al. Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma. J Clin Microbiol. 1991; 29(11): 2528-34[PubMed]
  • 18. Hsu HH, Wright TL, Luba D, Martin M, Feinstone SM, Garcia G, et al. Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction. Hepatology. 1991; 14(5): 763-7[PubMed]
  • 19. Ogasawara S, Kage M, Kosai K, Shimamatsu K, Kojiro M. Hepatitis C virus RNA in saliva and breastmilk of hepatitis C carrier mothers. Lancet. 1993; 341(8844): 561[PubMed]
  • 20. Ohto H, Terazawa S, Sasaki N, Sasaki N, Hino K, Ishiwata C, et al. Transmission of hepatitis C virus from mothers to infants. The Vertical Transmission of Hepatitis C Virus Collaborative Study Group. N Engl J Med. 1994; 330(11): 744-50[DOI][PubMed]
  • 21. Kiyosawa K, Sodeyama T, Tanaka E, Nakano Y, Furuta S, Nishioka K, et al. Hepatitis C in hospital employees with needlestick injuries. Ann Intern Med. 1991; 115(5): 367-9[PubMed]
  • 22. Wilkins T, Malcolm JK, Raina D, Schade RR. Hepatitis C: diagnosis and treatment. Am Fam Physician. 2010; 81(11): 1351-7[PubMed]
  • 23. Ozaras R, Tahan V. Acute hepatitis C: prevention and treatment. Expert Rev Anti Infect Ther. 2009; 7(3): 351-61[DOI][PubMed]
  • 24. Halliday J, Klenerman P, Barnes E. Vaccination for hepatitis C virus: closing in on an evasive target. Expert Rev Vaccines. 2011; 10(5): 659-72[DOI][PubMed]
  • 25. Torresi J, Johnson D, Wedemeyer H. Progress in the development of preventive and therapeutic vaccines for hepatitis C virus. J Hepatol. 2011; 54(6): 1273-85[DOI][PubMed]
  • 26. Ilyas JA, Vierling JM. An overview of emerging therapies for the treatment of chronic hepatitis C. Clin Liver Dis. 2011; 15(3): 515-36[DOI][PubMed]
  • 27. Chronic Hepatitis C Virus Advances in Treatment, Promise for the Future. 2011; : 4
  • 28. Stimac D, Bradaric N, Milic S. [Hepatitis C--who should be treated?]. Acta Med Croatica. 2009; 63(5): 403-8[PubMed]
  • 29. Hepatitis C and CAM What the Science Says. 2011;
  • 30. Khattak MN, Akhtar S, Mahmud S, Roshan TM. Factors influencing Hepatitis C virus sero-prevalence among blood donors in north west Pakistan. J Public Health Policy. 2008; 29(2): 207-25[DOI][PubMed]
  • 31. Ali SS, Ali IS, Aamir AH, Jadoon Z, Inayatullah S. Frequency of hepatitis C infection in diabetic patients. J Ayub Med Coll Abbottabad. 2007; 19(1): 46-9[PubMed]
  • 32. Ray Kim W. Global epidemiology and burden of hepatitis C. Microbes Infect. 2002; 4(12): 1219-25[PubMed]
  • 33. Media centre Hepatitis C. 2012;
  • 34. US News . 2012;
  • 35. Oxfam GB. Flooding in Pakistan Emergencies . 2010;
  • 36. Pakistan floods coverage: Blogs : Concern Worldwide. 2010;
  • 37. Bodeen C. Asia flooding plunges millions into misery. 2010;
  • 38. Lo Re V, 3rd, Kostman JR. Management of chronic hepatitis C. Postgrad Med J. 2005; 81(956): 376-82[DOI][PubMed]
  • 39. Ali A, Ahmed H, Idrees M. Molecular epidemiology of Hepatitis C virus genotypes in Khyber Pakhtoonkhaw of Pakistan. Virol J. 2010; 203: 1-7
  • 40. Idrees M, Riazuddin S. Frequency distribution of hepatitis C virus genotypes in different geographical regions of Pakistan and their possible routes of transmission. BMC Infect Dis. 2008; 8: 69
  • 41. Waqar M, Rehman H, Khan AU, Noor AA, Ali A, Wasim M, et al. Frequency Distribution of Hepatitis C Virus Genotypes in District Karachi, Pakistan. J Gastroentrol Hepatol Res. 2013; 3(4): 937-8
  • 42. Ahmad W, Ijaz B, Javed TF, Jahan S, Shahid I, Khan FM, et al. HCV genotype distribution and possible transmission risks in Lahore, Pakistan. World J Gastroenterol. 2010; 16: 4321-8
  • 43. Ali A, Nisar M, Ahmad H, Saif N, Idrees M, Bajwa MA. Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan. Virol J. 2011; 8(466)
  • 44. Muhammad N, Jan MA. Frequency of hepatitis “C” in Buner, NWFP. J Coll Physicians Surg Pak. 2005; 15: 11-4
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