Cite Score:
0.73
ELSEVIER SCOPUS

Prevalence of Hepatitis A in Iranian Patients with Chronic Liver Disease

AUTHORS

Ahmad Shavakhi 1 , Mohammad Hossein Somi 1 , * , Sara Farhang 1 , Golnar Majidi 1 , Taraneh Majidi 1 , Ali Asghar Pouri 1

AUTHORS INFORMATION

1 Liver and Gastrointestinal Diseases Research Center (LRGDC), Tabriz University of Medical Sciences, Tabriz, IR Iran

How to Cite: Shavakhi A, Somi M H, Farhang S, Majidi G, Majidi T, et al. Prevalence of Hepatitis A in Iranian Patients with Chronic Liver Disease, Arch Clin Infect Dis. Online ahead of Print ; 3(4):189-192.

ARTICLE INFORMATION

Archives of Clinical Infectious Diseases: 3 (4); 189-192
Article Type: Research Article

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background: Acute hepatitis A in patients with chronic liver diseases (CLD) may lead to a more severe outcome for which routine vaccination is recommended in many regions. Nevertheless, studies of HAV seroprevalence and exposure predictors in populations with CLD are scanty in our region.

Patients and methods: We studied 200 patients with CLD between September 2005 and September 2006. Patients were stratified on the basis of age, gender, size of family, place of residency and etiology of liver disease. The HAV seroprevalence in patients with CLD was compared with age- and sex-matched controls. Independent predictors of HAV exposure were identified by logistic regression analysis.

Results: Of 200 patients, HAV seroprevalence was available for 190 (96.5%). Hepatitis B and C, alcohol, autoimmune hepatitis and Wilsons disease were the causes of CLD. Most of the seronegative patients aged 10-20 years. The overall HAV seroprevalence was 97.3% in controls. None of the risk factors were identified as independent predictors.

Conclusion: Age stratified seroprevalence of HAV in patients with CLD is close to that of the general population. High prevalence of HAV must be considered in vulnerable travelers to our country.

Keywords

Hepatitis A, Seroprevalence, Chronic liver disease

© 0, Archives of Clinical Infectious Diseases. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF

COMMENTS

LEAVE A COMMENT HERE: