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The Antimicrobial Activity of Ferula Gummosa on Bacterial Strains Isolated from Patients with Gastroenteritis

AUTHORS

Fariba Fayaz 2 , Sara Rahmati Roodsari 1 , * , Latif Gachkar 1 , Bita Pourkaveh 1 , Hajieh Ghasemian Safaei 3

2 Assistant Professor of Department of Microbiology, Shahid Beheshti University of Medical Sciences ,Tehran Iran

1 Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran

3 Associated Professor of Department of Microbiology, Isfahan University of Medical Sciences, Isfahan, IR Iran

How to Cite: Fayaz F, Rahmati Roodsari S, Gachkar L, Pourkaveh B, Ghasemian Safaei H. The Antimicrobial Activity of Ferula Gummosa on Bacterial Strains Isolated from Patients with Gastroenteritis, Arch Clin Infect Dis. Online ahead of Print ; 6(Suppl):21-4.

ARTICLE INFORMATION

Archives of Clinical Infectious Diseases: 6 (Suppl); 21-4
Article Type: Research Article

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Abstract

Objective: Ferula gummosa grows as a native plant in different parts of Iran and has been used for treatment of some infections such as UTI since ancient times. Present study is planned to show the antibacterial effect of this herb on bacteria isolated from infectious diarrhea.

Patients and Methods: Extracts of the plant were achieved using maceration method. The concentration of 0.2gr/ml was used against pathogenic bacteria causing gastroenteritis; isolated from patients admitted to Shahid Beheshti University of Medical Sciences Hospitals and also minimum inhibitory concentration (MIC) of the extract was determined.

Results: The highest value of MIC was due to Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae and even Pseudomonas with 1/1024 dilution liter. Three antibiotics of tetracycline, trimethoprim and ciprofloxacin were also tested against the bacteria. The highest MIC was in 1/1000 mg/ml of ciprofloxacin and was against Pseudomonas aeruginosa and Serratia marcescens with MIC dilution of 21 .

Conclusion: According to our findings, it is recommended to use Ferula gummosa extract, as a herbal alternative treatment, in more investigations to prove its treatment effects on infections.

Keywords

MIC, pathogenic bacteria, infectious diarrhea, Ferula gummosa

© 0, Archives of Clinical Infectious Diseases. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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