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Comparison of Rosa Nutkana Sepal Extract with Synthetic Antibiotics for Treatment of Methicillin Resistant Staphylococcus Aureus Isolated from Patients with Sty

AUTHORS

Gita Eslami 1 , * , Sudabe Taheri 2 , Sayed Abdol Majid Ayatollahi 3 , Ghazaleh Malek 4 , Fatemeh fallah 1 , Bita Pourkaveh 1

1 Infections Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Science, Tehran, IR Iran

2 Tutor of Microbiology Department, faculty of Medicine, Shahid Beheshti University of Medical Science, Tehran, IR Iran

3 Professor of Pharmacognosy, Phytochemistery ResearchCenter, Shahid Beheshti University of Medical Science, Tehran, IR Iran

4 Dr. in pharmacy, Tehran Azad Eslamic University, Faculty of Pharmaceutical Sciences

How to Cite: Eslami G, Taheri S, Ayatollahi S A M, Malek G, fallah F, et al. Comparison of Rosa Nutkana Sepal Extract with Synthetic Antibiotics for Treatment of Methicillin Resistant Staphylococcus Aureus Isolated from Patients with Sty, Arch Clin Infect Dis. Online ahead of Print ; 6(Suppl):7-11.

ARTICLE INFORMATION

Archives of Clinical Infectious Diseases: 6 (Suppl); 7-11
Article Type: Research Article

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Abstract

Objective: This research was carried out to compare antibacterial effect of Rosa nutkana sepal extract with synthetic antibiotics on methicillin resistant staphylococcus aureus (MRSA) bacteria isolated from patients with sty.

Patients and Methods: This descriptive study was done in 2009 at remedial center of Shahid Beheshti University and sampling was performed from patients suffering from sty using sterile soap. After preparation of Rosa nutkana sepal extract and after determining bacteria type, antibiogram test was used to determine bacterial resistance and sensitivity to cephalothin, co-amoxiclav, amoxicillin and tetracycline, as well as to the extract. Disc diffusion and agar dilution were used for this purpose. The area of non-growth resulting from antibiotic discs was compared with of the extract.

Results: In this study, 31% of samples were reported to be MRSA. MRSA in 1/128 concentration of extract was sensitive in minimum inhibitory concentration (MIC) test. In disc diffusion test, Staphylococcus aureus was 100% sensitive to the extract, 15.8% to cephalothin, 26.3% to tetracycline, 31.6% to co-amoxiclav and 100% resistant to amoxicillin. Furthermore, there was not any microbial growth in agar dilution method (nutrient agar environment and 0.01% extract of plant sample). Moreover, there was not any microbial growth in plates containing Pseudomonas aeruginosa and Candida albicans.

Conclusion: Rosa nutkana sepal extract with antibiotics can be an important combination for treatment of sty infection.

Keywords

Extract, Sepal, Rosa nutkana, Resistance, Sensitivity

© 0, Archives of Clinical Infectious Diseases. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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