Archives of Clinical Infectious Diseases

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Frequency Distribution of Various Oncogenes of Human Papillomavirus in Genital Cancerous Lesions in the City of Gorgan

Sanaz Purmomeni 1 and Leila Fozouni ORCID 1 , *
Authors Information
1 Department of Biology, Gorgan Branch, Islamic Azad University, Gorgan, Iran
Article information
  • Archives of Clinical Infectious Diseases: 14 (3); e81909
  • Published Online: June 16, 2019
  • Article Type: Research Article
  • Received: July 9, 2018
  • Revised: March 11, 2019
  • Accepted: April 28, 2019
  • DOI: 10.5812/archcid.81909

To Cite: Purmomeni S, Fozouni L. Frequency Distribution of Various Oncogenes of Human Papillomavirus in Genital Cancerous Lesions in the City of Gorgan, Arch Clin Infect Dis. Online ahead of Print ; 14(3):e81909. doi: 10.5812/archcid.81909.

Copyright © 2019, Archives of Clinical Infectious Diseases. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Sohrabi A, Mirab-Samiee S, Modarresi MH, Izadimood N, Azadmanesh K, Rahnamaye-Farzami M. Development of in-house multiplex real time PCR for human papillomavirus genotyping in Iranian women with cervical cancer and cervical intraepithelial neoplasia. Asian Pac J Cancer Prev. 2014;15(15):6257-61. doi: 10.7314/apjcp.2014.15.15.6257. [PubMed: 25124608].
  • 2. Roberts CC, Tadesse AS, Sands J, Halvorsen T, Schofield TL, Dalen A, et al. Detection of HPV in Norwegian cervical biopsy specimens with type-specific PCR and reverse line blot assays. J Clin Virol. 2006;36(4):277-82. doi: 10.1016/j.jcv.2006.03.013. [PubMed: 16765639].
  • 3. Allameh T, Moghim S, Asadi-Zeidabadi M. A survey on the prevalence of high-risk subtypes of human papilloma virus among women with cervical neoplasia in Isfahan University of Medical Science. Arch Gynecol Obstet. 2011;284(6):1509-13. doi: 10.1007/s00404-011-1863-4. [PubMed: 21387088].
  • 4. Stanley MA, Pett MR, Coleman N. HPV: From infection to cancer. Biochem Soc Trans. 2007;35(Pt 6):1456-60. doi: 10.1042/BST0351456. [PubMed: 18031245].
  • 5. Wacher C, Muller M, Hofer MJ, Getts DR, Zabaras R, Ousman SS, et al. Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. J Virol. 2007;81(2):860-71. doi: 10.1128/JVI.01167-06. [PubMed: 17079283]. [PubMed Central: PMC1797448].
  • 6. Dunne EF, Unger ER, Sternberg M, McQuillan G, Swan DC, Patel SS, et al. Prevalence of HPV infection among females in the United States. JAMA. 2007;297(8):813-9. doi: 10.1001/jama.297.8.813. [PubMed: 17327523].
  • 7. Weaver BA, Feng Q, Holmes KK, Kiviat N, Lee SK, Meyer C, et al. Evaluation of genital sites and sampling techniques for detection of human papillomavirus DNA in men. J Infect Dis. 2004;189(4):677-85. doi: 10.1086/381395. [PubMed: 14767822].
  • 8. Hyo-Sung H, Misun P, Sei-Young L. Distribution and prevalence of human papillomavirus genotypes in routine Pap smear of 2,470 Korean women determined by DNA chip. Cancer Epidemiol Biomarkers Prev. 2004;13(12):2153-6.
  • 9. Li S, Meng YH, Ting H, Shen J, Ma D. Clinical significance of human papilloma virus infection in the cervical lesions. Front Med China. 2010;4(3):264-70. doi: 10.1007/s11684-010-0094-6. [PubMed: 21191829].
  • 10. McFarlane-Anderson N, Bazuaye PE, Jackson MD, Smikle M, Fletcher HM. Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women. BMC Womens Health. 2008;8:9. doi: 10.1186/1472-6874-8-9. [PubMed: 18513406]. [PubMed Central: PMC2430195].
  • 11. Castle PE, Giuliano AR. Chapter 4: Genital tract infections, cervical inflammation, and antioxidant nutrients--assessing their roles as human papillomavirus cofactors. J Natl Cancer Inst Monogr. 2003;(31):29-34. doi: 10.1093/oxfordjournals.jncimonographs.a003478. [PubMed: 12807942].
  • 12. Barghi MR, Rahjoo T, Borghei M, Hosseini-Moghaddam SM, Amani D, Farrokhi B. Association between the evidence of human papilloma virus infection in bladder transitional cell carcinoma in men and cervical dysplasia in their spouses. Arch Iran Med. 2012;15(9):572-4. [PubMed: 22924378].
  • 13. Youshya S, Purdie K, Breuer J, Proby C, Sheaf MT, Oliver RT, et al. Does human papillomavirus play a role in the development of bladder transitional cell carcinoma? A comparison of PCR and immunohistochemical analysis. J Clin Pathol. 2005;58(2):207-10. doi: 10.1136/jcp.2004.017152. [PubMed: 15677544]. [PubMed Central: PMC1770580].
  • 14. Boonyanurak P, Panichakul S, Wilawan K. Prevalence of high-risk human papillomavirus infection (HPV) and correlation with postmenopausal hormonal therapy in Thai women aged more than 45 years old. J Med Assoc Thai. 2010;93(1):9-16. [PubMed: 20196405].
  • 15. Hashemi Dezfoli SM, Ghane M. [Detection and prevalence of herpes simplex virus and papilloma virus from bladder cancer tissue by PCR from Doctor Gharazi Hospital, Malayer - Hamadan in 2014]. Iran J Med Microbiol. 2016;10(1):56-65. Persian.
  • 16. Smith JS, Lindsay L, Hoots B, Keys J, Franceschi S, Winer R, et al. Human papillomavirus type distribution in invasive cervical cancer and high-grade cervical lesions: A meta-analysis update. Int J Cancer. 2007;121(3):621-32. doi: 10.1002/ijc.22527. [PubMed: 17405118].
  • 17. Hamkar R, Mokhtari Azad T, Mahmoodi M, Seyedirashti S, Severini A, Nategh R. Prevalence of human papillomavirus in Mazandaran province, Islamic Republic of Iran. East Mediterr Health J. 2002;8(6):805-11. [PubMed: 15568458].
  • 18. Munoz N, Bosch FX, de Sanjose S, Herrero R, Castellsague X, Shah KV, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med. 2003;348(6):518-27. doi: 10.1056/NEJMoa021641. [PubMed: 12571259].
  • 19. Haghshenas MR, Mousavi T, Moosazadeh M, Afshari M. Human papillomavirus and breast cancer in Iran: A meta- analysis. Iran J Basic Med Sci. 2016;19(3):231-7. [PubMed: 27114791]. [PubMed Central: PMC4834111].
  • 20. Nadji SA, Mokhtari-Azad T, Mahmoodi M, Yahyapour Y, Naghshvar F, Torabizadeh J, et al. Relationship between lung cancer and human papillomavirus in north of Iran, Mazandaran province. Cancer Lett. 2007;248(1):41-6. doi: 10.1016/j.canlet.2006.05.016. [PubMed: 16814459].
  • 21. Aghakhani A, Hamkar R, Parvin M, Ghavami N, Nadri M, Pakfetrat A, et al. The role of human papillomavirus infection in prostate carcinoma. Scand J Infect Dis. 2011;43(1):64-9. doi: 10.3109/00365548.2010.502904. [PubMed: 20662618].
  • 22. Moradi A, Bakhshandeh Nosrat S, Besharat S. Molecular epidemiology of high-risk types of human papillomaviruses (16, 18) in Pap smear, the North East of Iran. Iran J Cancer Prev. 2011;4(3):135-40. [PubMed: 26328053]. [PubMed Central: PMC4551297].
  • 23. Jabarpour M, Esmaeili M, Dastran A. [Multiplex PCR to determine the types of human papillomavirus oncogenes in cervical cancer lesions in North West Iran]. Iran J Infect Dis. 2008;41(13):29-34. Persian.
  • 24. Hassani M, Salehian P, PoorAzar SH. [Evaluation of the presence of human papillomavirus in various types of cervical lesions by means of molecular techniques]. Sarem J. 2012;1(2):47-51. Persian.
  • 25. Keyhani E, Kohannia N, Izadimood N, Keyhkhaee MR, Najmabadi H. [The prevalence of human papilloma virus(HPV)in malignant cervical lesion, using multiplex PCR]. Tehran Univ Med J. 2006;64(3):95-101. Persian.

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