The epidemic of tuberculosis that mimics systemic lupus erythematosus


Mycobacterium tuberculosis (MTB) is one of the most common causes of widespread granulomatous disease, especially in developing countries where people don’t have access to joint supplements. Widespread tuberculosis should be considered in the differential diagnosis of a wide range of clinical symptoms (1). This represents approximately 1-3% of all cases of tuberculosis (2). Disseminated tuberculosis accounted for 1.8% of tuberculosis cases reported in the United States in 2006 (3, 4). Fever, weight loss, and hematological abnormalities are common outbreaks of this infection, but they can cause abnormal medical problems. In disseminated tuberculosis, severe immune hemolytic anemia (5), lymphadenopathy with systemic lymphadenopathy and hepatosplenomegaly (6), dactylitis in immunosuppressed patients (7) and prostate lesions (8) have been reported. It has been. Tuberculosis and systemic lupus erythematosus (SLE) show similar symptoms such as fever, myalgia, arthralgia / arthritis, skin rash, and multi-organ lesions (9). This study reports cases of disseminated tuberculosis with long-term fever and SLE criteria.

Study Findings

Introduction: Mycobacterium tuberculosis (MTB) is one of the most common causes of widespread granulomatous disease, especially in developing countries.

Case presentation: Introduce a patient with an abnormal type of tuberculosis who has been misdiagnosed as another common disorder such as infective endocarditis or collagen vascular disease. Pathological examinations have helped us make decisions.

Discussion: MTB occurs in the clinical manifestations of proteins and can cause some laboratory deficits. In endemic areas, surveillance is essential to control this infection.


  1. Lawn SD, Zumla AI. Tuberculosis. The Lancet. 2011; 378(9785) : 57 -722. 
  2. Golden MP, Vikram HR. Extrapulmonary tuberculosis: an overview. Am Fam Physician. 2005; 72(9) : 1761 -8 [PubMed] 3. 
  3. Reported tuberculosis in the United States, 2006. 2007; 4. 
  4. Peto HM, Pratt RH, Harrington TA, LoBue PA, Armstrong LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993-2006. Clin Infect Dis. 2009; 49(9) : 1350 -7 [DOI][PubMed] 5. 
  5. Kuo PH, Yang PC, Kuo SS, Luh KT. Severe immune hemolytic anemia in disseminated tuberculosis with response to antituberculosis therapy. Chest. 2001; 119(6) : 1961 -3 [PubMed] 6. 
  6. Kushwaha R, Singhal S, Verma S. Disseminated tuberculosis mimicking lymphoma. Calicut Med J. 2008; 6(2) 7. 
  7. Agarwal S, Caplivski D, Bottone EJ. Disseminated tuberculosis presenting with finger swelling in a patient with tuberculous osteomyelitis: a case report. Ann Clin Microbiol Antimicrob. 2005; 4 : 18 [DOI][PubMed] 8. 
  8. Mittal R, Sudha R, Veeraraghavan M, Murugan S, Adikrishnan S, Krishnakanth M, et al. Disseminated tuberculosis with involvement of prostate–a case report. Indian J Tuberc. 2010; 57(1) : 48 -52 [PubMed] 9. 
  9. Elkayam O, Caspi D, Lidgi M, Segal R. Auto-antibody profiles in patients with active pulmonary tuberculosis. Int J Tuberc Lung Dis. 2007; 11(3) : 306 -10 [PubMed]